Clozapine-related seizures: experience with 5,629 patients.


We reviewed the incidence, clinical features, and management of all clozapine-related seizures in 5,629 patients monitored by the Clozaril Patient Management System, during the first 6 months after marketing. Seventy-one patients had generalized tonic-clonic seizures yielding a frequency of 1.3%. One patient had myoclonic seizures prior to generalization… (More)


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@article{Pacia1994ClozapinerelatedSE, title={Clozapine-related seizures: experience with 5,629 patients.}, author={Steven V. Pacia and Orrin Devinsky}, journal={Neurology}, year={1994}, volume={44 12}, pages={2247-9} }