CloudBurst: highly sensitive read mapping with MapReduce

@article{Schatz2009CloudBurstHS,
  title={CloudBurst: highly sensitive read mapping with MapReduce},
  author={Michael C. Schatz},
  journal={Bioinformatics},
  year={2009},
  volume={25},
  pages={1363 - 1369}
}
MOTIVATION Next-generation DNA sequencing machines are generating an enormous amount of sequence data, placing unprecedented demands on traditional single-processor read-mapping algorithms. CloudBurst is a new parallel read-mapping algorithm optimized for mapping next-generation sequence data to the human genome and other reference genomes, for use in a variety of biological analyses including SNP discovery, genotyping and personal genomics. It is modeled after the short read-mapping program… CONTINUE READING
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