Clotiapine compared with chlorpromazine in chronic schizophrenia

  title={Clotiapine compared with chlorpromazine in chronic schizophrenia},
  author={V. Geller and Igor Gorzaltsan and Tatiana Shleifer and R. Belmaker and Y. Bersudsky},
  journal={Schizophrenia Research},
  • V. Geller, Igor Gorzaltsan, +2 authors Y. Bersudsky
  • Published 2005
  • Medicine, Psychology
  • Schizophrenia Research
  • OBJECTIVES Clotiapine is a classic neuroleptic with a chemical structure similar to clozapine. It was said that patients unresponsive to other neuroleptics respond to clotiapine although it causes extrapyramidal syndromes (EPS) like other typical neuroleptics. We conducted a study of clotiapine vs. chlorpromazine in severe chronic active psychotic hospitalized schizophrenia patients. METHODS The design was double-blind crossover of clotiapine vs chlorpromazine. No washout was necessary from… CONTINUE READING
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