Closure of supporting cell scar formations requires dynamic actin mechanisms

@article{Hordichok2007ClosureOS,
  title={Closure of supporting cell scar formations requires dynamic actin mechanisms},
  author={Andrew J Hordichok and Peter S Steyger},
  journal={Hearing Research},
  year={2007},
  volume={232},
  pages={1-19}
}
In many vertebrate inner ear sensory epithelia, dying sensory hair cells are extruded, and the apices of surrounding supporting cells converge to re-seal the epithelial barrier between the electrochemically-distinct endolymph and perilymph. These cellular mechanisms remain poorly understood. Dynamic microtubular mechanisms have been proposed for hair cell extrusion; while contractile actomyosin-based mechanisms are required for cellular extrusion and closure in epithelial monolayers. The… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…