Clostridium thermocellum ATCC27405 transcriptomic, metabolomic and proteomic profiles after ethanol stress

@inproceedings{Yang2011ClostridiumTA,
  title={Clostridium thermocellum ATCC27405 transcriptomic, metabolomic and proteomic profiles after ethanol stress},
  author={Shihui Yang and Richard J Giannone and Lezlee T Dice and Zamin K. Yang and Nancy L. Engle and Timothy J. Tschaplinski and Robert L. Hettich and Steven D Brown},
  booktitle={BMC Genomics},
  year={2011}
}
Clostridium thermocellum is a candidate consolidated bioprocessing biocatalyst, which is a microorganism that expresses enzymes for both cellulose hydrolysis and its fermentation to produce fuels such as lignocellulosic ethanol. However, C. thermocellum is relatively sensitive to ethanol compared to ethanologenic microorganisms such as yeast and Zymomonas mobilis that are used in industrial fermentations but do not possess native enzymes for industrial cellulose hydrolysis. In this study, C… CONTINUE READING

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Mutant alcohol dehydrogenase leads to improved ethanol tolerance in Clostridium thermocellum.

Proceedings of the National Academy of Sciences of the United States of America • 2011
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