Clostridium difficile infection.
@article{Leffler2015ClostridiumDI, title={Clostridium difficile infection.}, author={Daniel A. Leffler and John Thomas Lamont}, journal={The New England journal of medicine}, year={2015}, volume={372 16}, pages={ 1539-48 } }
This article reviews the pathogenesis, epidemiology, diagnosis, and treatment of this nosocomial and potentially fatal infectious diarrhea, as well as the associated risk factors. New treatments include fecal microbiota transplantation for disease that is resistant to vancomycin.
1,138 Citations
The Challenge of Clostridium difficile Infection
- Medicine, BiologyNorth Carolina Medical Journal
- 2016
This commentary provides an update regarding the epidemiology, diagnosis, current recommended management, and challenges surrounding C. difficile infection.
Clostridium Difficile Infection—Diagnosis, Treatment and Prevention
- Medicine
- 2020
C. difficile is a leading cause of hospital associated gastrointestinal illness, placing high economic burden on the healthcare system and it frequently causes large hospital outbreaks.
Trends in Incidence and Clinical Outcomes of Clostridioides difficile Infection, Hong Kong
- Medicine, BiologyEmerging infectious diseases
- 2021
Surveillance of C. difficile infections suggests correlation of incidence to antibiotic stewardship programs, and further research is needed to establish a cause-and-effect relationship.
Mechanisms of Colonization Resistance Against Clostridioides difficile.
- Biology, MedicineThe Journal of infectious diseases
- 2020
Commensal gut microbes are critical for providing colonization resistance against C. difficile, and can be leveraged as non-antibiotic alternative therapeutics for the prevention and treatment of CDI.
Community-acquired Clostridium difficile infection.
- Medicine, BiologyCanadian family physician Medecin de famille canadien
- 2017
The bacterium Clostridium difficile is transmitted by the fecal-oral route and can cause illness ranging from diarrhea to colitis, toxic megacolon, and death.
The outcomes of Clostridioides difficile infection in inpatient liver transplant population
- Medicine, BiologyTransplant infectious disease : an official journal of the Transplantation Society
- 2021
The aim is to determine the inpatient outcomes of liver transplant patients with Clostridioides difficile infection (CDI) and trends in the last few years.
Clostridium difficile and Antibiotic-associated Diarrhea
- MedicineIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
- 2020
Clostridium difficile and Antibiotic-associated Diarrhea and Indian J Crit Care Med 2020;24(Suppl 4):S162–S167.
"Allogenic Fecal Microbiota Transplantation in Clostridioides Difficile Infection: A Case Series in Mexico"
- Biology, MedicineBiomedical Journal of Scientific & Technical Research
- 2021
Clostridioides difficile is a gram-positive, spore-forming bacterium that produces toxins that causes diarrhoea, fever, and rash in people and animals infected with the bacterium.
Clostridium difficile Infection.
- Medicine, BiologyJournal of the Pediatric Infectious Diseases Society
- 2013
A brief synopsis of a few recent publications that focused on C difficile infections, including comments regarding the implications within pediatric infectious diseases.
Association Between Outpatient Antibiotic Prescribing Practices and Community-Associated Clostridium difficile Infection
- MedicineOpen forum infectious diseases
- 2015
A modest, 10% reduction in outpatient antibiotic prescribing among U.S. adults could result in a substantial 17% reduction in Clostridium difficile infections that originate in the community.
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