Clostridium difficile infection prevention: biotherapeutics, immunologics, and vaccines.

@article{Gerding2012ClostridiumDI,
  title={Clostridium difficile infection prevention: biotherapeutics, immunologics, and vaccines.},
  author={Dale N. Gerding},
  journal={Discovery medicine},
  year={2012},
  volume={13 68},
  pages={75-83}
}
We are in the midst of a resurgence of Clostridium difficile infection (CDI) in North America and Europe for which morbidity and mortality are higher than ever seen. C. difficile has risen in frequency to become the most common healthcare-associated infection pathogen, exceeding methicillin-resistant Staphylococcus aureus in many hospitals. Protection against CDI is thought to be mediated first by the normal bacterial microbiota, supplemented by an adaptive immune antibody response directed… CONTINUE READING
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