Clostridium difficile associated infection, diarrhea and colitis.

  title={Clostridium difficile associated infection, diarrhea and colitis.},
  author={Perry Hookman and Jamie S Barkin},
  journal={World journal of gastroenterology},
  volume={15 13},
A new, hypervirulent strain of Clostridium difficile, called NAP1/BI/027, has been implicated in C. difficile outbreaks associated with increased morbidity and mortality since the early 2000s. The epidemic strain is resistant to fluoroquinolones in vitro, which was infrequent prior to 2001. The name of this strain reflects its characteristics, demonstrated by different typing methods: pulsed-field gel electrophoresis (NAP1), restriction endonuclease analysis (BI) and polymerase chain reaction… CONTINUE READING
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