Clostridium difficile and the microbiota.

  title={Clostridium difficile and the microbiota.},
  author={Anna M Seekatz and Vincent B Young},
  journal={The Journal of clinical investigation},
  volume={124 10},
Clostridium difficile infection (CDI) is the leading health care-associated illness. Both human and animal models have demonstrated the importance of the gut microbiota's capability of providing colonization resistance against C. difficile. Risk factors for disease development include antibiotic use, which disrupts the gut microbiota, leading to the loss of colonization resistance and subsequent CDI. Identification of the specific microbes capable of restoring this function remains elusive… CONTINUE READING
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