Clostridium difficile Infections in Children: Impact of the Diagnostic Method on Infection Rates.


BACKGROUND Polymerase chain reaction (PCR) assays based on the detection of the toxin B gene are replacing enzyme-linked immunosorbent assay (ELISA)-based toxin production detection or cell cytotoxicity assay in most laboratories. OBJECTIVE To determine the proportion of pediatric patients diagnosed with Clostridium difficile infection by PCR who would have… (More)
DOI: 10.1017/ice.2016.123