Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection

@article{Zhu2018ClostridioidesDB,
  title={Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection},
  author={D. Zhu and Joseph A Sorg and X. Sun},
  journal={Frontiers in Cellular and Infection Microbiology},
  year={2018},
  volume={8}
}
  • D. Zhu, Joseph A Sorg, X. Sun
  • Published 2018
  • Biology, Medicine
  • Frontiers in Cellular and Infection Microbiology
  • Clostridioides difficile is a Gram-positive, spore-forming, toxin-producing anaerobe, and an important nosocomial pathogen. Due to the strictly anaerobic nature of the vegetative form, spores are the main morphotype of infection and transmission of the disease. Spore formation and their subsequent germination play critical roles in C. difficile infection (CDI) progress. Under suitable conditions, C. difficile spores will germinate and outgrow to produce the pathogenic vegetative form. During… CONTINUE READING

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