Closed head injury—an inflammatory disease?

@article{Schmidt2005ClosedHI,
  title={Closed head injury—an inflammatory disease?},
  author={Oliver I. Schmidt and Christoph Eckhard Heyde and Wolfgang Ertel and Philip F. Stahel},
  journal={Brain Research Reviews},
  year={2005},
  volume={48},
  pages={388-399}
}
Closed head injury (CHI) remains the leading cause of death and persisting neurological impairment in young individuals in industrialized nations. Research efforts in the past years have brought evidence that the intracranial inflammatory response in the injured brain contributes to the neuropathological sequelae which are, in large part, responsible for the adverse outcome after head injury. The presence of hypoxia and hypotension in the early resuscitative period of brain-injured patients… CONTINUE READING

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