Closed-form two-locus sampling distributions: accuracy and universality.

  title={Closed-form two-locus sampling distributions: accuracy and universality.},
  author={Paul A. Jenkins and Yun S. Song},
  volume={183 3},
Sampling distributions play an important role in population genetics analyses, but closed-form sampling formulas are generally intractable to obtain. In the presence of recombination, there is no known closed-form sampling formula that holds for an arbitrary recombination rate. However, we recently showed that it is possible to obtain useful closed-form sampling formulas when the population-scaled recombination rate rho is large. Specifically, in the case of the two-locus infinite-alleles model… CONTINUE READING
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λ(a, b, c) = − θA(c−

  • Jenkins, Song
  • 2009
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