Closed-chest small animal model to study myocardial infarction in an MRI environment in real time

Abstract

Current models for real time study of the effects of myocardial ischemia/reperfusion have major limitations and confounders. Confounders include the surgical stresses of a thoracotomy and abnormal physiology of an open chest. The need to reposition the animal interferes with the study of the early changes associated with ischemia. Direct comparison of pre… (More)
DOI: 10.1007/s10554-014-0539-0

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