Closed-channel culture system for efficient and reproducible differentiation of human pluripotent stem cells into islet cells.

@article{Hirano2017ClosedchannelCS,
  title={Closed-channel culture system for efficient and reproducible differentiation of human pluripotent stem cells into islet cells.},
  author={Kunio Hirano and Shuhei Konagaya and Alexander Turner and Yuichiro Noda and Shigeru Kitamura and Hidetoshi Kotera and Hiroji Iwata},
  journal={Biochemical and biophysical research communications},
  year={2017},
  volume={487 2},
  pages={
          344-350
        }
}
Human pluripotent stem cells (hPSCs) are thought to be a promising cell-source solution for regenerative medicine due to their indefinite proliferative potential and ability to differentiate to functional somatic cells. However, issues remain with regard to achieving reproducible differentiation of cells with the required functionality for realizing human transplantation therapies and with regard to reducing the potential for bacterial or fungal contamination. To meet these needs, we have… CONTINUE READING
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