Closed-Loop Insulin Delivery Using a Subcutaneous Glucose Sensor and Intraperitoneal Insulin Delivery

@inproceedings{Renard2010ClosedLoopID,
  title={Closed-Loop Insulin Delivery Using a Subcutaneous Glucose Sensor and Intraperitoneal Insulin Delivery},
  author={Eric Renard and J{\'e}r{\^o}me Place and Martin Cantwell and Hugues Chevassus and Cesar C. Palerm},
  booktitle={Diabetes care},
  year={2010}
}
OBJECTIVE Attempts to build an artificial pancreas by using subcutaneous insulin delivery from a portable pump guided by an subcutaneous glucose sensor have encountered delays and variability of insulin absorption. We tested closed-loop intraperitoneal insulin infusion from an implanted pump driven by an subcutaneous glucose sensor via a proportional-integral-derivative (PID) algorithm. RESEARCH DESIGN AND METHODS Two-day closed-loop therapy (except for a 15-min pre-meal manual bolus) was… CONTINUE READING
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Complications (DCCT/EDIC) Study Research Group: Intensive diabetes management and cardiovascular disease in patients with type 1 diabetes

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