Close linkage between X-linked ectodermal dysplasia and a cloned DNA sequence detecting a two allele restriction fragment length polymorphism in the region Xp11-q12

Abstract

EDA (ectodermal dysplasia, anhidrotic) is an X-linked recessive disorder characterized by hypohidrosis, hypoor anodontia, and hypotrichosis. A possible linkage between the gene for EDA and a number of restriction fragment length polymorphisms (RFLPs) spread over the X chromosome was investigated in two Danish families segregating EDA. No recombination… (More)
DOI: 10.1007/BF00282550

Topics

3 Figures and Tables

Cite this paper

@article{Klvraa1986CloseLB, title={Close linkage between X-linked ectodermal dysplasia and a cloned DNA sequence detecting a two allele restriction fragment length polymorphism in the region Xp11-q12}, author={Steen K\olvraa and Torben Arvid Kruse and Pamela K. Jensen and Kirsten H. Linde and S\oren R. Vestergaard and Lars Bolund}, journal={Human Genetics}, year={1986}, volume={74}, pages={284-287} }