Close kinship of human 20α‐hydroxysteroid dehydrogenase gene with three aldo‐keto reductase genes

@article{Nishizawa2000CloseKO,
  title={Close kinship of human 20$\alpha$‐hydroxysteroid dehydrogenase gene with three aldo‐keto reductase genes},
  author={M Nishizawa and Tatsuya Nakajima and Katsuhiko Yasuda and Hideharu Kanzaki and Yasuyuki Sasaguri and K. Watanabe and Sumiyo Ito},
  journal={Genes to Cells},
  year={2000},
  volume={5}
}
20α‐Hydroxysteroid dehydrogenase (HSD) is a member of the aldo‐keto reductase (AKR) superfamily and catalyses the reaction of progesterone to the inactive form 20α‐hydroxyprogesterone. Progesterone plays an important role in the maintenance of pregnancy, and, in rodents, plasma progesterone levels decrease abruptly just before parturition. The induction of 20α‐HSD is thought to be responsible for the decrease in plasma progesterone at term. High homology between human 20α‐HSD [AKR 1C1] cDNA… Expand
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TLDR
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Notice of RetractionA Cluster of Five Hydroxysteroid Dehydrogenase Genes Belonging to the Aldo-Keto Reductase Supergene Family on Human Chromosome 10
  • Moli Huang, H. Duan
  • Biology
  • 2011 5th International Conference on Bioinformatics and Biomedical Engineering
  • 2011
TLDR
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TLDR
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TLDR
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TLDR
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During storage at 4 degrees C, the 17 beta-hydroxysteroid dehydrogenase activity of human placental microsomes with estradiol-17 beta was more stable than that with testosterone. In order to evaluateExpand
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TLDR
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TLDR
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TLDR
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