Close juxtapositions between LHRH immunoreactive neurons and substance P immunoreactive axons in the human diencephalon.

@article{Duds2002CloseJB,
  title={Close juxtapositions between LHRH immunoreactive neurons and substance P immunoreactive axons in the human diencephalon.},
  author={Bertalan Dud{\'a}s and Istv{\'a}n J. Merchenthaler},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2002},
  volume={87 6},
  pages={2946-53}
}
LHRH release is induced by substance P (SP) in the rat hypothalamus. Recent immunocytochemical studies indicate that SP-immunoreactive axons synapse on LHRH neurons in the diencephalon of the rat, but this phenomenon has not yet been demonstrated in human. Therefore, in the present study we visualized the SP- and LHRH-immunoreactive (IR) elements in the human diencephalon and evaluated the close juxtapositions between them. The distribution of LHRH- and SP-IR sites were investigated in… CONTINUE READING
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