Close and focal contact adhesions of fibroblasts to a fibronectin-containing matrix.

@article{Lark1985CloseAF,
  title={Close and focal contact adhesions of fibroblasts to a fibronectin-containing matrix.},
  author={Michael W. Lark and John Laterra and Lloyd A. Culp},
  journal={Federation proceedings},
  year={1985},
  volume={44 2},
  pages={394-403}
}
The fibroblast cell line Balb/c 3T3 makes both close and tight-focal adhesive contacts with the plasma fibronectin (pFn)-coated tissue culture substratum. Detachment of these cells mediated by ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid leaves tight-focal contacts and a subset of close contacts as substratum-attached material (SAM). The enrichment of heparan sulfate (HS) proteoglycan (HS-PG) in SAM under specific attachment conditions, as well as the recent… CONTINUE READING
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