Cloning of the oxidative stress-responsive genes in Caenorhabditis elegans.

  title={Cloning of the oxidative stress-responsive genes in Caenorhabditis elegans.},
  author={Sumino Yanase and Norihisa Ishi},
  journal={Journal of radiation research},
  volume={40 1},
Defense systems against free radicals and reactive oxygen species minimize the lethal and mutagenic consequences of these destructive agents. To investigate the genetic response to oxidative stress in a eukaryote, we cloned and characterized oxidative stress-responsive genes by comparing gene expression in the free-living nematode Caenorhabditis elegans under atmospheric conditions and high oxygen concentrations using a method of RNA arbitrarily primed polymerase chain reaction method (RAP-PCR… CONTINUE READING
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