Cloning of the mucosal addressin MAdCAM-1 from human brain: identification of novel alternatively spliced transcripts.

@article{Leung1996CloningOT,
  title={Cloning of the mucosal addressin MAdCAM-1 from human brain: identification of novel alternatively spliced transcripts.},
  author={Euphemia Y Leung and John Greene and Jian Ni and Lynn Raymond and Klaus Lehnert and Ries J Langley and Geoffrey Wayne Krissansen},
  journal={Immunology and cell biology},
  year={1996},
  volume={74 6},
  pages={
          490-6
        }
}
The mucosal addressin cell adhesion molecule-1 (MAdCAM-1), expressed selectively on high endothelial venules (HEV) and lamina propria venules, directs lymphocyte traffic by binding the lymphocyte Peyer's patch adhesion molecule-1 (LPAM-1, alpha 4 beta 7). Full-length DNA encoding human MAdCAM-1 was obtained by combining sequences from an expressed sequence tag (EST) identified in an early stage human brain cDNA library, a polymerase chain reaction-derived clone, and a MAdCAM-1 genomic clone… CONTINUE READING