Cloning of the complete rat immunoglobulin delta gene: evolutionary implications.

@article{Zhao2003CloningOT,
  title={Cloning of the complete rat immunoglobulin delta gene: evolutionary implications.},
  author={Yaofeng Zhao and Lennart Hammarstr{\"o}m},
  journal={Immunology},
  year={2003},
  volume={108 3},
  pages={288-95}
}
The recent discovery of a Cdelta encoding gene in artiodactyls has raised questions regarding the evolution of the gene. In the present study, we have analysed the complete rat Cdelta gene both at the cDNA and genomic levels, showing that the rat Cdelta gene is structurally similar to the corresponding mouse gene. Analysis of the rat immunoglobulin D heavy chain cDNA tail sequences, revealed two transcripts for the secreted form with varying sizes of their 3' untranslated region (UTR… CONTINUE READING