Cloning of rat brain interleukin-18 cDNA


The interleukin-1 (IL-1) family comprises IL-1α and IL-1β and an endogenous IL-1 receptor antagonist (IL-1ra).1 IL-1 has diverse actions in the brain and has been implicated in both acute and chronic neurodegeneration.1,2 However, neither IL-1α nor IL-1β are neurotoxic per se in vivo, so other IL-1 related ligands may be important in neurodegeneration. The… (More)
DOI: 10.1038/


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@article{Culhane1998CloningOR, title={Cloning of rat brain interleukin-18 cDNA}, author={Aidan Culhane and Melissa D Hall and Nancy J. Rothwell and Giamal N. Luheshi}, journal={Molecular Psychiatry}, year={1998}, volume={3}, pages={362-366} }