Cloning of leukemia associated gene LRP16 in acute myeloid leukemia

@inproceedings{Wei2000CloningOL,
  title={Cloning of leukemia associated gene LRP16 in acute myeloid leukemia},
  author={Han Wei and Plas General},
  year={2000}
}
Objective:The purpose of this paper is to clone novel leukemia associated gene in acute myeloid leukemia (AML).Methods:The Restriction landmark genomic scanning (RLGS),Southern blot, Northern blot and rapid amplification of cDNA end (RACE) technique were performed on genomic DNA or RNA from AML and normal bone marrow (BM) samples.Results:An abnormal 2948bp fragment due to a distinct DNA methylation on NotI site in relapse sample from AML was cloned. The Sequence represents part of a new gene… CONTINUE READING

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