Cloning of human heparan sulfate proteoglycan core protein, assignment of the gene (HSPG2) to 1p36.1----p35 and identification of a BamHI restriction fragment length polymorphism.

@article{Kallunki1991CloningOH,
  title={Cloning of human heparan sulfate proteoglycan core protein, assignment of the gene (HSPG2) to 1p36.1----p35 and identification of a BamHI restriction fragment length polymorphism.},
  author={Pekka Kallunki and R. L. Eddy and Mary G. Byers and Marjo Kestil{\"a} and T. B. Shows and K. Tryggvason},
  journal={Genomics},
  year={1991},
  volume={11 2},
  pages={389-96}
}
We have isolated a cDNA coding for the core protein of the large basement membrane heparan sulfate proteoglycan (HSPG) from a human fibrosarcoma cell (HT1080) library. The library was screened with a mouse cDNA probe and one clone obtained, with a 1.5-kb insert, was isolated and sequenced. The sequence contained an open reading frame coding for 507 amino… CONTINUE READING