Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes.

@article{Nonoguchi1999CloningOH,
  title={Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes.},
  author={Kohsuke Nonoguchi and Kazuyuki Itoh and Jing Hui Xue and H Tokuchi and Hiroyuki Nishiyama and Yayoi Kaneko and Koichi Tatsumi and Hiroaki Okuno and Kiyotaka Tomiwa and Jun Fujita},
  journal={Gene},
  year={1999},
  volume={237 1},
  pages={21-8}
}
In mice, the Hsp110/SSE family is composed of the heat shock protein (Hsp)110/105, Apg-1 and Apg-2. In humans, however, only the Hsp110/105 homolog has been identified as a member, and two cDNAs, Hsp70RY and HS24/p52, potentially encoding proteins structurally similar to, but smaller than, mouse Apg-2 have been reported. To clarify the membership of Hsp110 family in humans, we isolated Apg-1 and Apg-2 cDNAs from a human testis cDNA library. The human Apg-1 was 100% and 91.8% identical in length… CONTINUE READING

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