Cloning of an X. laevis gene expressed during early embryogenesis coding for a peptide region homologous to Drosophila homeotic genes

@article{Carrasco1984CloningOA,
  title={Cloning of an X. laevis gene expressed during early embryogenesis coding for a peptide region homologous to Drosophila homeotic genes},
  author={Andr{\'e}s E. Carrasco and William McGinnis and W. J. Gehring and Eddy M. De Robertis},
  journal={Cell},
  year={1984},
  volume={37},
  pages={409-414}
}
A Xenopus laevis gene was cloned on the basis of cross-homology to a region conserved between several Drosophila homeotic genes. It was shown to be expressed during early development, starting at late gastrulation and producing three transcripts under specific temporal control. The frog gene contains a region coding for 60 amino acids, which is extremely conserved when compared to Drosophila homeotic genes in the region of the homeo domain. Southern blot analysis indicates that there are at… Expand
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