Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

@article{Yamauchi2003CloningOA,
  title={Cloning of adiponectin receptors that mediate antidiabetic metabolic effects},
  author={Toshimasa Yamauchi and Junji Kamon and Yusuke Ito and Atsushi Tsuchida and Takehiko Yokomizo and Shunbun Kita and Takuya Sugiyama and Makoto Miyagishi and Kazuo Hara and Masaki Tsunoda and Koji Murakami and Toshiaki Ohteki and Shoko Uchida and Sato Takekawa and Hironori Waki and Nelson Hirokazu Tsuno and Yoichi Shibata and Yasuo Terauchi and Philippe Froguel and Kazuyuki Tobe and Shigeo Koyasu and Kazunari Taira and Toshio Kitamura and Takao Shimizu and Ryozo Nagai and Takashi Kadowaki},
  journal={Nature},
  year={2003},
  volume={423},
  pages={762-769}
}
Corrigendum (2004)10.1038/nature03091Adiponectin (also known as 30-kDa adipocyte complement-related protein; Acrp30) is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Levels of adiponectin in the blood are decreased under conditions of obesity, insulin resistance and type 2 diabetes. Administration of adiponectin causes glucose-lowering effects and ameliorates insulin resistance in mice. Conversely, adiponectin-deficient mice exhibit insulin… Expand

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