Cloning of a novel orphan receptor (GCNF) expressed during germ cell development.

  title={Cloning of a novel orphan receptor (GCNF) expressed during germ cell development.},
  author={F Chen and Austin John Cooney and Yongqing Wang and Simon W. Law and Bert W O'malley},
  journal={Molecular endocrinology},
  volume={8 10},
We have cloned a novel member of the nuclear receptor superfamily that has been identified from complementary DNA libraries derived from mouse tissues using a low stringency cross hybridization strategy. The deduced protein sequence contains 495 amino acids and consists of the characteristic DNA-binding and ligand-binding domains of the nuclear receptor superfamily. The primary sequence of this new orphan is distinct from those of previously cloned members and subgroups. Analysis of the DNA… CONTINUE READING
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