Cloning of a neonatal calcium atpase isoform (SERCA 1B) from extraocular muscle of adult blue marlin (Makaira nigricans).

@article{Londraville2000CloningOA,
  title={Cloning of a neonatal calcium atpase isoform (SERCA 1B) from extraocular muscle of adult blue marlin (Makaira nigricans).},
  author={Richard Lyle Londraville and Thorsten Cramer and Jens P C Franck and Alexa Tullis and Barbara A Block},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology},
  year={2000},
  volume={127 2},
  pages={223-33}
}
Complete cDNAs for the fast-twitch Ca2+ -ATPase isoform (SERCA 1) were cloned and sequenced from blue marlin (Makaira nigricans) extraocular muscle (EOM). Complete cDNAs for SERCA 1 were also cloned from fast-twitch skeletal muscle of the same species. The two sequences are identical over the coding region except for the last five codons on the carboxyl end; EOM SERCA 1 cDNA codes for 996 amino acids and the fast-twitch cDNAs code for 991 aa. Phylogenetic analysis revealed that EOM SERCA 1… CONTINUE READING