Cloning of a human nucleoside transporter implicated in the Cellular uptake of adenosine and chemotherapeutic drugs

@article{Griffiths1997CloningOA,
  title={Cloning of a human nucleoside transporter implicated in the Cellular uptake of adenosine and chemotherapeutic drugs},
  author={M. N. Griffiths and Nick J Beaumont and Sylvia Y. M. Yao and Manickavasagam Sundaram and Christine E. Boumah and Anthony Davies and Francis Y. P. Kwong and Imogen R. Coe and Carol E. Cass and James D. Young and Stephen A. Baldwin},
  journal={Nature Medicine},
  year={1997},
  volume={3},
  pages={89-93}
}
In most mammalian Cells nucleoside uptake occurs primarily via broad-specificity, es (e, equilibrative; s, sensitive to NBMPR inhibition) transporters that are potentlyinhibited by nitrobenzylthioinosine (NBMPR)1. These transporters are essential for nucleotide synthesis by salvage pathways in hemopoietic and other Cells that lack de novo pathways and are… CONTINUE READING