Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter.

@article{Wells1992CloningOA,
  title={Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter.},
  author={Rebecca G. Wells and Ana M. Pajor and Yoshikatsu Kanai and Eric Turk and Ernest M. Wright and Matthias A. Hediger},
  journal={The American journal of physiology},
  year={1992},
  volume={263 3 Pt 2},
  pages={
          F459-65
        }
}
We have used low-stringency screening with the human intestinal Na(+)-glucose cotransporter SGLT1 to isolate a 2,271-nucleotide cDNA (Hu14) from human kidney. This clone, which encodes a 672-residue protein, is 59% identical at the amino acid level to SGLT1 and has a similar number and arrangement of predicted membrane-spanning regions. It also shares significant sequence identity with other Na(+)-coupled transporters. Northern blot analysis suggests strong expression of Hu14 in kidney, but… 
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