Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block.

Abstract

Ionotropic receptors for gamma-aminobutyric acid (GABA) are important to inhibitory neurotransmission in the mammalian retina, mediating GABAA and GABAC responses. In many species, these responses are blocked by the convulsant picrotoxinin (PTX), although the mechanism of block is not fully understood. In contrast, GABAC responses in the rat retina are… (More)

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@article{Zhang1995CloningOA, title={Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block.}, author={D. Zhang and Z. H. Pan and X Zhang and Amy D Brideau and S. Lipton}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1995}, volume={92 25}, pages={11756-60} }