Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

@article{Farrow1995CloningOA,
  title={Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K},
  author={Stuart N. Farrow and J. H. White and Isabelle Martinou and Thomas Raven and K Tao Pun and Christine J. Grinham and J C Martinou and Robin Brown},
  journal={Nature},
  year={1995},
  volume={374},
  pages={731-733}
}
A NUMBER of DNA viruses carry apoptosis-inhibiting genes which enable the virus to escape from the host reponse1–5. The adenovirus E1B 19K protein can inhibit apoptosis induced by El A, tumour-necrosis factor-α, FAS antigen and nerve growth factor deprivation6–9. The molecular basis of this inhibition remains poorly understood, but the fact that protection… CONTINUE READING