Cloning of a Rab3 isotype predominantly expressed in adipocytes.

  title={Cloning of a Rab3 isotype predominantly expressed in adipocytes.},
  author={Giulia Baldini and Tobias M. Hohl and Herbert Y. Lin and Harvey F. Lodish},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={89 11},
We have isolated the cDNA for Rab3D, an additional member of the small molecular weight GTP-binding protein family. Rab3D message is abundant in mouse adipocytes. It is increased during differentiation of 3T3-L1 cells into adipocytes, temporally coincident with the appearance of the insulin-sensitive glucose transporter GLUT4. Rab3D is a close homolog of Rab3A, which is found on the cytoplasmic surface of neurosecretory vesicles and which may be involved in their regulated secretion. Since our… CONTINUE READING

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