Cloning debate: Stem-cell researchers must stay engaged

  title={Cloning debate: Stem-cell researchers must stay engaged},
  author={Martin F. Pera and Alan Trounson},
Recent developments have rekindled the ethical debate over human cloning. This is no time for complacency, caution Martin Pera and Alan Trounson. 

Stem cells for spine surgery.

Stem cell therapy has received the attention of spinal surgeons due to its potential benefits in the treatment of neural damage, muscle trauma, disk degeneration and its potential contribution to bone fusion.

The STAP Flap, the CIRM Squirm, and Lab Morality

“Reputation in science is everything,” said Alan Trounson to David Cyranoski. “Once gone, it's extremely hard to get back.”1As a bioethicist, I have to say I admire the worldwide scientific communi...

Transgenic animal technology: Recent advances and applications: A Review

This review focuses on various methods of transgenesis and its application, which will provide solutions for drug research, xenotransplantation, disease resistance and tissue repair etc.



Finding the niche for human somatic cell nuclear transfer

Does human somatic cell nuclear transfer have a future after the discovery of induced pluripotent stem cells?

Genomic stability in reprogramming.

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants

The potential of nuclear genome transfer between unfertilized oocytes of two donors to prevent the transmission of mitochondrial mutations is demonstrated and mitochondrial respiratory chain enzyme activities and oxygen consumption rates are indistinguishable from controls.

Towards germline gene therapy of inherited mitochondrial diseases

Although some ST oocytes displayed abnormal fertilization, remaining embryos were capable of developing to blastocysts and producing embryonic stem cells similar to controls.

Offspring from Oocytes Derived from in Vitro Primordial Germ Cell–like Cells in Mice

It is shown that female (XX) embryonic stem cells and induced pluripotent stem cells in mice are induced into primordial germ cell–like cells (PGCLCs), which, when aggregated with female gonadal somatic cells as reconstituted ovaries, undergo X-reactivation, imprint erasure, and cyst formation, and exhibit meiotic potential.

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

Of these genes, BCL2L1 is a strong candidate for driving culture adaptation of ES cells, and single-nucleotide polymorphism analysis revealed that they included representatives of most major ethnic groups.

And then there were two: use of hESC lines

volume 27 number 8 AuGuST 2009 nature biotechnology Using data on cell line shipments obtained from HSCI and WiCell—which curates the NSCB—we see that lines have been neither uniformly available nor

Time for an Arab astronomy renaissance Arab Muslim countries need a new generation of observatories to rejoin the forefront

  • Nature 493,
  • 2013