Cloning and sequencing of junction fragment with exons 45-54 deletion of dystrophin gene.

Abstract

OBJECTIVE To study the mechanisms of dystrophin gene deletion, the junction fragment with exons 45-54 deletion were cloned and sequenced. METHODS A Duchenne muscular dystrophy (DMD) patient with exons 45-54 deletion has been substantiated by PCR amplification of the exons. Then we used a PCR-based genome-walking method for localizing the breakpoints in… (More)

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@article{Zhong2006CloningAS, title={Cloning and sequencing of junction fragment with exons 45-54 deletion of dystrophin gene.}, author={Min Zhong and Su-Yue Pan and Bing-xun Lu and Wei Li}, journal={Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics}, year={2006}, volume={23 2}, pages={138-41} }