Cloning and regulation of cornifin beta, a new member of the cornifin/spr family. Suppression by retinoic acid receptor-selective retinoids.

@article{Austin1996CloningAR,
  title={Cloning and regulation of cornifin beta, a new member of the cornifin/spr family. Suppression by retinoic acid receptor-selective retinoids.},
  author={Steve J. Austin and Wakako Fujimoto and Keith W. Marvin and T. M. Vollberg and Laszlo Lorand and Anton M Jetten},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 7},
  pages={
          3737-42
        }
}
In this study, we describe the isolation and characterization of a cDNA clone C12 that encodes a new member of the cornifin/small proline-rich protein (spr) family, which we have named cornifin beta. C12 encodes a 1.1-kilobase pair mRNA and a 24.3-kDa cytosolic protein with a high proline content (19%). Its total amino acid sequence exhibits a 37-66% identity while the first 30 amino acids at the amino terminus are 87% identical to that of members of the cornifin family. At its carboxyl… CONTINUE READING
BETA