Cloning and partial sequencing of a novel human activin receptor-like kinase.

Abstract

Receptors for the transforming growth factor (TGF)-beta receptor superfamily are transmembrane protein serine/threonine kinases. By using a polymerase chain reaction (PCR)-based strategy to screen for the protein kinase sequences, we isolated a novel complementary DNA (cDNA) clone from a human breast carcinoma and a human brain cDNA libraries. The PCR… (More)

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