Cloning and in vitro antiapoptotic effects of pig FLIPs.


INTRODUCTION Cellular FLICE-like protein (cFLIP) inhibits death receptor-mediated apoptosis signal transduction, such as that induced by Fas and TNFR. The present study examined the role of antiapoptotic molecules to protect pig cells from human natural killer (NK) cells in vitro, as a model of delayed-type xenograft rejection. METHODS Pig FLIPs were… (More)
DOI: 10.1016/j.transproceed.2008.08.024