Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5

@article{Smith2002CloningAG,
  title={Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5},
  author={Jeffrey B. Smith and David J. Wadleigh and Yao Xiao Xia and Rebecca A. Mar and Harvey R. Herschman and Aldons J. Lusis},
  journal={Immunogenetics},
  year={2002},
  volume={54},
  pages={599-603}
}
LPS-induced CXC chemokine (LIX) is a murine chemokine similar to two human chemokines, ENA-78 (CXCL5) and GCP-2 (CXCL6). To clarify the relationship of LIX to human ENA-78 and GCP-2, we cloned and mapped the LIX gene. The organization of the LIX gene (Scyb5) is similar to those of the human ENA-78 (SCYB5) and GCP-2 (SCYB6) genes. The intron-exon boundaries of the three genes are exactly conserved, and the introns have similar sizes. The first 100 bp of the 5′ flanking regions are highly similar… CONTINUE READING

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Chemokines: immunology's high impact factors

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