Cloning and genomic characterization of LST1: a new gene in the human TNF region

  title={Cloning and genomic characterization of LST1: a new gene in the human TNF region},
  author={I. Holzinger and A. D. Baey and G. Messer and G. Kick and H. Zwierzina and E. Weiss},
  • I. Holzinger, A. D. Baey, +3 authors E. Weiss
  • Published 2004
  • Biology, Medicine
  • Immunogenetics
  • The leucocyte specific transcript — 1 (LST1) represents the human homolog of the mouse B144 transcript, encoded within the tumor necrosis factor (TNF) region of the human major histocompatibility complex class III interval. The gene is localized about 4 kilobases upstream of the lymphotoxin ß gene. It spans a polymorphic genomic region encompassing the microsatellites TNFd and TNFe in intron 3 and a polymorphic Pvu II restriction site 260 base pairs downstream of the polyadenylation signal… CONTINUE READING
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