Cloning and functional expression of an MIP (AQP0) homolog from killifish (Fundulus heteroclitus) lens.

Abstract

The major intrinsic protein (MIP) of lens fiber cells is a member of the aquaporin (AQP) water channel family. The protein is expressed at very high levels in lens fiber cells, but its physiological function is unclear. By homology to known AQPs, we have cloned a full-length cDNA encoding an MIP from the lens of killifish (Fundulus heteroclitus). The… (More)

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