Cloning and functional expression of a cardiac inward rectifier K+ channel.

@article{Ishii1994CloningAF,
  title={Cloning and functional expression of a cardiac inward rectifier K+ channel.},
  author={Kazuhiro Ishii and Toshio Yamagishi and Norio Taira},
  journal={FEBS letters},
  year={1994},
  volume={338 1},
  pages={107-11}
}
We have isolated a cDNA coding for an inward rectifier K+ channel (RBHIK1) from rabbit heart. The cloned cDNA encodes a protein of 427 amino acids with two putative transmembrane segments. The primary structure of RBHIK1 is highly homologous to that of IRK1 which is an inward rectifier K+ channel recently cloned from mouse macrophage by expression cloning… CONTINUE READING