Cloning and functional characterization of the human 5‐HT2B serotonin receptor

@article{Schmuck1994CloningAF,
  title={Cloning and functional characterization of the human 5‐HT2B serotonin receptor},
  author={Karin Schmuck and Christoph Ullmer and Peter Engels and Hermann Lübbert},
  journal={FEBS Letters},
  year={1994},
  volume={342}
}

Gene Structure, Expression, and 5-HT2B Receptor Signaling

The complexity of its signaling in relation with its expression, including in various types of cancer cells, is developed and discussed.

The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors

These findings confirm the sequence of the human 5‐HT2B receptor and they demonstrate that the receptor has a widespread tissue distribution and suggest that there are differences in ligand affinities between different species homologues of the receptor.

Development and Characterization of Monoclonal Antibodies Specific to the Serotonin 5-HT2A Receptor

  • C. WuE. Yoder S. Singh
  • Biology
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • 1998
The development and characterization of MAbs specific to the serotonin 5-HT2A receptor are reported, which showed differential staining in various regions of the rat brain, varying from regions with no staining to regions of intense reactivity.

Localization of the gene for the human serotonin 5-HT(2B) receptor to chromosome 2.

A 483 bp Bgl II/Sal I repeat free fragment was isolated from the vector containing the human serotonin 5-HT(2B) receptor and revealed 100 percent concordance with location of the gene for this 5- HT receptor variant at chromosome 2.
...

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