Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter.

@article{Adra1987CloningAE,
  title={Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter.},
  author={Chaker N. Adra and Poppo H. Boer and Michael W McBurney},
  journal={Gene},
  year={1987},
  volume={60 1},
  pages={65-74}
}
We report the cloning of the mouse pgk-1 gene encoding the somatic cell isoform of the enzyme phosphoglycerate kinase. The gene is contained within a 16-kb region of the X chromosome and is interrupted by at least ten introns. The promoter region of the pgk-1 gene is rich in G and C nucleotides and contains five copies of the hexadeoxynucleotide, GGGCGG, the potential binding site for the Sp 1 transcription factor, a CCAAT sequence, but no TATA box. This promoter functions following DNA… CONTINUE READING
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