Cloning and expression of AQP3, a water channel from the medullary collecting duct of rat kidney.

@article{Echevarria1994CloningAE,
  title={Cloning and expression of AQP3, a water channel from the medullary collecting duct of rat kidney.},
  author={M. Acosta - Echevarria and Erich E. Windhager and Suresh S. Tate and Gustavo Frindt},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 23},
  pages={
          10997-1001
        }
}
The terminal part of the inner medullary collecting duct exhibits a high degree of water permeability that is independent of increased intracellular cAMP and not accounted for by the activity of the known renal epithelial water channels CHIP28 (28-kDa channel-forming integral protein) and WCH-CD (collecting duct water channel protein). Starting with rat kidney papilla mRNA, reverse transcription PCR was performed with degenerate primers assuming that the putative channel would be a member of… CONTINUE READING
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