Cloning and characterization of the homologous genes of firefly luciferase in the mealworm beetle, Tenebrio molitor.

@article{Oba2006CloningAC,
  title={Cloning and characterization of the homologous genes of firefly luciferase in the mealworm beetle, Tenebrio molitor.},
  author={Yuichi Oba and Mitsunori Sato and Satoshi Inouye},
  journal={Insect molecular biology},
  year={2006},
  volume={15 3},
  pages={293-9}
}
Three homologous genes of firefly luciferase were cloned from the non-luminous beetle Tenebrio molitor. Three gene products for homologues, TmLL-1, TmLL-2 and TmLL-3, showed fatty acyl-coenzyme A (acyl-CoA) synthetic activity, but not luciferase activity with firefly luciferin. The transcripts were detected through the developmental stages in T. molitor. These results suggested that firefly luciferase was evolved from a fatty acyl-coenzyme A synthetase by gene duplications in the insect. 

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