Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family.

@article{Sugimoto1998CloningAC,
  title={Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family.},
  author={Rie Sugimoto and Y Yae and Mina Akaiwa and Shoji Kitajima and Yasutaka Shibata and Hideyo Sato and Jun Hirata and Kazuo Okochi and Kenji Izuhara and Naotaka Hamasaki},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 33},
  pages={20721-7}
}
The Hakata antigen is a novel, thermolabile beta2-macroglycoprotein that reacts with sera from patients suffering from systemic lupus erythematosus. In this study we present the structure and the function of the Hakata antigen. We have identified cDNA clones encoding the Hakata antigen and analyzed its function. The cDNA included a possible open reading frame of 897 nucleotides, encoding 299 amino acids. The Hakata antigen consisted of a collagen-like domain in the middle section and a… CONTINUE READING

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